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Panel: Sahar Osman-Sypher
Media: Bryan Goodman

Aliphatic diisocyanates (ADI) are chemical intermediates used to make polyurethane (PU) products relied upon by many businesses and consumers worldwide. They are part of the diisocyanates (DII) family of chemicals, which have been used since the late 1940s. This website focuses on the three primary aliphatic diisocyanates used in PU production:

  • Hexamethylene diisocyanate (HDI)
  • Methylene dicyclohexyl diisocyanate or hydrogenated MDI (HMDI)
  • Isophorone diisocyanate (IPDI)

Aliphatic diisocyanates primary are used in paint and surface coatings such as automotive and truck refinishing, as well as industrial, maintenance and performance coatings. For example, durable coatings made with ADI can protect military, commercial and passenger planes from UV damage. They are often used to make coatings needed to combat harsh conditions, such as in military, marine or infrastructure applications (i.e. bridges).

Visit Fast Facts and Figures to find out more about the benefits of ADI chemistry.

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Benefits and Uses of Aliphatic Diisocyanates

Aliphatic diisocyanates are building blocks for color-stable polyurethane coatings, paints, elastomers and thermoplastics.

Infographic on Declining Asthma Cases

Decrease in diisocyanate-related occupational asthma aided by enhanced industry stewardship.


News & Resources

View our resource center to find press releases, testimonies, infographics and more.


Jobs and Economic Impact

More than 800,000 Americans rely on jobs in the chemistry industry—earning 47 percent more than the average manufacturing wage.